Business hates uncertainty. When deciding how and where to spend, that can be what pushes them to pick the next best option for how they use their capital. A province that may not stay a part of its country will be toxic to a lot of businesses considering major investments.
Smith needs to see this as a warning shot across the bow. She could say Alberta’s residents and businesses need and deserve clarity, actually stake out not just her own but her party’s position, and call a referendum for, say, the fall to settle the matter for the foreseeable future. Get the answer and move on with whatever direction that points the provincial government.